Zhang Yang Lab 

PUBLICATIONS
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Book chapters 

1.       Zhang, Yang , and Huanghe Yang. "Quantification of Trophoblast Syncytialization by Fluorescent Membrane Labeling." Trophoblasts: Methods and Protocols.

 New York, NY: Springer US, 2023. 99-104.


Papers

1.       A.J. Lowry, P. Liang, M. Song, Y. Wan, Z. Pei, H. Yang, Y. Zhang (2024) TMEM16 and OSCA/TMEM63 proteins share a conserved potential to permeate ions and phospholipids

eLife 13:RP96957 https://doi.org/10.7554/eLife.96957.3

2.       P. Liang1, Y. Zhang1, Y.S. Wan, S. Ma, P. Dong, A.J. Lowry, S.J. Francis, S. Khandelwal, M. Delahunty, M.J. Telen, J.J. Strouse, G.M. Arepally, H. Yang, Deciphering and Disrupting PIEZO1-TMEM16F Interplay in Hereditary Xerocytosis, Blood 143(4):357-69 (2024)

3.       Y. Zhang, P. Liang, L. Yang K. Shan, L. Feng, Y. Chen, W. Liedtke, C. B. Coyne, H. Yang, Functional coupling between TRPV4 channel and TMEM16F modulates human trophoblast fusion. eLife 11: e78840 (2022) 

4.       P. Dong, Y. Zhang, M. A. Mikati, J. Cui, H. Yang, Neuronal mechanism of a BK channelopathy in absence epilepsy and dyskinesia. PNAS 119 (12) e2200140119, 2022 

5.       Y. Zhang, T. Le, R. Grabau, Z. Mohseni, H. Kim, D. R. Natale, L. Feng, H. Pan, H. Yang, TMEM16F phospholipid scramblase mediates trophoblast fusion and placental development. Science Advances 6, eaba0310, 2020 

6.       Y. Zhang, Z. Zhang, S. Xiao, J. Tien, S. Le, T. Le, L. Y. Jan, H. Yang, Inferior olivary TMEM16B mediates cerebellar motor learning, Neuron, 95:1103–1111, 2017 

7.       C. Liao, Y. Zhang, C. Fan, L. E. Herring, J. Liu, J. W. Locasale, G. Zurlo, L. Hu, J. M. Simon, T. S. Ptacek, O. Pugovics, E. Loza, H. Yang, C. M. Perou, and Q. Zhang, Identification of BBOX1 as a therapeutic target in triple-negative breast cancer, Cancer Discovery 10(11): 1706-1721, 2020

8.       X. Yang, Y. Zhang, K. Zhao, Y. Zhao, Y. Liu, H. Gong, Q. Luo, and D. Zhu, Skull Optical Clearing Solution for Enhancing Ultrasonic and Photoacoustic Imaging., IEEE Transactions on Medical imaging, 35(8):1903-6, 2016 

9.       Y. Zhang, H. Yang, A simple and robust fluorescent labeling method to quantify trophoblast fusion, Placenta, 77:16-18, 2019 

10.     T. Le, S. Le, Y. Zhang, P. Liang, H. Huang, Evidence that polyphenols do not inhibit the phospholipid scramblase TMEM16F. Journal of Biological Chemistry, jbc-AC120, 2020

11.     T. Le, Z. Jia, S. C. Le, Y. Zhang, J. Chen, H. Yang, An inner activation gate controls TMEM16F phospholipid scrambling, Nature Communications, 10: 1846, 2019 

12.     S. Wei, Q. Xu, Y. Zhang, Y. Zhan, W. Zheng, and L. Song. Fully integrated reflection-mode photoacoustic, two-photon, and second harmonic generation microscopy in vivo, Scientific Reports, 6: 32240, 2016.